Clostridium difficile infection, an increasingly prevalent and virulent condition, is often resistant to treatment. Standard antibiotic therapy is rarely efficient when used to treat recurrent C. difficile infection. Fecal microbiota transplantation (FMT) is a safe, effective and inexpensive treatment that has a cure rate of about 90%, according to clinical trials and reports. This approach may also be applicable in treating ulcerative colitis, a type of inflammatory bowel disease, on the basis of the restoration of flora imbalances. Additionally, recent data suggests that a disproportion in composition of the gut microbiome may contribute to obesity. FMT, may restore a healthy balance. Using information from Touro College’s database, this article discusses the reason behind the success of fecal microbiota transplantation when used to treat Clostridium difficile infection and ulcerative colitis. The effect of diet, environment and geography on the bacterial flora is also explored.
Steinberg, R. (2016). Mechanism of Fecal Bacteriotherapy in Treating Clostridium Difficile Infection and GI Tract Disorders. The Science Journal of the Lander College of Arts and Sciences, 9 (2). Retrieved from http://touroscholar.touro.edu/cgi/viewcontent.cgi?article=1052&context=sjlcas