Cyclocryotherapy employs temperatures as low as −112 °F (−80 °C) to destroy the ciliary body, thereby decreasing aqueous production and intraocular pressure. Secondary to the risk of significant intraocular inflammation, loss of vision, and phthisis, cyclocryotherapy may often be used as a last-line treatment option for uncontrolled or refractory glaucoma.
Wandel T, Nattis AS. Cyclocryotherapy. In: Rosenberg ED, Nattis A, Nattis RJ, editors. Operative dictations in ophthalmology. Cham, Switzerland: Springer International Publishing; 2017. pp. 159-60.