NYMC Faculty Publications

Devices for Autonomic Regulation Therapy in Heart Failure With Reduced Ejection Fraction

Journal Title

Cardiology in Review

First Page

43

Last Page

49

Document Type

Article

Publication Date

January 2018

Department

Medicine

Abstract

Heart failure (HF) is associated with significant morbidity and mortality and an increasing economic burden. The persistence of HF's risk factors, coupled with an aging population, also leads to an increase in its incidence and prevalence. It is well established that sympathetic hyperactivity and parasympathetic withdrawal are instrumental in the development and worsening of HF. Therefore, restoring autonomic balance to the cardiovascular system is an attractive therapeutic approach. The following is a review of current clinical trials of device-based autonomic regulation therapy in the management of HF with a reduced ejection fraction.

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