Tuberculin-Active Carbohydrate That Induces Inhibition of Macrophage Migration but Not Lymphocyte Transformation
A tuberculin carbohydrate fraction, GAE, in sensitized animals induced a delayed type of skin reactivity and inhibited the migration of macrophages but failed to stimulate lymphocyte transformation in vitro. Tuberculin protein-containing fractions were active in each test. These results show that in vitro lymphocyte transformation is not necessarily a corollary of delayed type hypersensitivity.
Chaparas, S., Thor, D., Godfrey, H., Baer, H., & Hedrick, S. (1970). Tuberculin-Active Carbohydrate That Induces Inhibition of Macrophage Migration but Not Lymphocyte Transformation. Science (New York, N.Y.), 170 (3958), 637-639. https://doi.org/10.1126/science.170.3958.637