NYMC Faculty Publications

Title

Guinea Pig Macrophage Agglutination Factor Is Antigenically Distinct From Migration Inhibition Factor and Immunoglobulin

Document Type

Article

Publication Date

October 1978

Department

Pathology

Abstract

Lymph node cells from guinea pigs with specific delayed hypersensitivity release macrophage agglutination (MAggF) and migration inhibition factors (MIF) upon exposure to antigen or concanavalin A in serum-free medium. MAggF in culture supernatants was absorbed neither by immunoabsorbents made with a rabbit anti-guinea pig lymphokine serum that removed MIF, nor by immunoabsorbents made with rabbit anti-guinea pig Ig. These results suggest that MAggF is antigenically distinct from MIF and Ig.

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