No Histologic Evidence of Foetal Cardiotoxicity Following Exposure to Maternal Hydroxychloroquine
It is currently recommended that hydroxychloroquine (HCQ) be maintained during pregnancy in patients with systemic lupus erythematosus. Recent data suggest that this Toll-like receptor inhibitor may also reduce the recurrence rate of anti-SSA/Ro associated congenital heart block (CHB). This case report describes a unique situation in which a CHB-afflicted, HCQ-exposed pregnancy was electively terminated. The heart did not reveal any characteristic features of cardiotoxicity, providing further evidence supporting the safety of foetal exposure to HCQ.
Friedman, D., Lovig, L., Halushka, M., Clancy, R. M., Izmirly, P. M., & Buyon, J. P. (2017). No Histologic Evidence of Foetal Cardiotoxicity Following Exposure to Maternal Hydroxychloroquine. Clinical and Experimental Rheumatology, 35 (5), 857-859. Retrieved from https://touroscholar.touro.edu/nymc_fac_pubs/230
Originally published in Clinical and Experimental Rheumatology, 35 (5), 857-859. The original material can be found here.