Is Doxycycline Appropriate for Routine Treatment of Young Children With Erythema Migrans?
The frequency of permanent staining of teeth of young children from doxycycline is thought to be lower than from older tetracyclines, but the precise risk is uncertain. Until more definitive data become available, doxycycline should not be used routinely to treat young children with erythema migrans, a manifestation of Lyme disease for which other antimicrobials are highly effective.
Wormser, G., Strle, F., & Shapiro, E. (2019). Is Doxycycline Appropriate for Routine Treatment of Young Children With Erythema Migrans?. The Pediatric Infectious Disease Journal, 38 (11), 1113-1114. https://doi.org/10.1097/INF.0000000000002453