Successful Liver Transplantation in a Patient Recovered From COVID-19
Transplantation in potential candidates who have recently recovered from COVID-19 is a challenge with uncertainties regarding the diagnosis, multi-organ systemic involvement, prolonged viral shedding in immunocompromised patients, and optimal immunosuppression. A 42 year male with alcoholic hepatitis underwent a successful deceased donor liver transplantation 71 days after the initial diagnosis of COVID-19. At the time of transplant, he was SARS-CoV-2 PCR negative for 24 days and had a MELD score of 33. His post-operative course was complicated by acute rejection which responded to intense immune-suppression using T-cell depletion and steroids. He was discharged with normal end-organ function and no evidence of any active infection including COVID-19. Prospective organ transplant recipients who have recovered from COVID-19 can be considered for transplantation after careful pre-transplant evaluation, donor selection, and individualized risk-benefit analysis.
Dhand, A., Bodin, R., Wolf, D. C., Schluger, A., Nabors, C., Nog, R., Diflo, T., & Nishida, S. (2021). Successful Liver Transplantation in a Patient Recovered From COVID-19. Transplant Infectious Disease, 23 (2), 13492-13492. https://doi.org/10.1111/tid.13492