NYMC Faculty Publications
Brain-heart Interactions in Traumatic Brain Injury
Journal Title
Cardiology in Review
First Page
279
Last Page
288
Document Type
Article
Publication Date
November 2017
Department
Surgery
Second Department
Medicine
Abstract
The cardiovascular manifestations associated with nontraumatic head disorders are commonly known. Similar manifestations have been reported in patients with traumatic brain injury (TBI); however, the underlying mechanisms and impact on the patient's clinical outcomes are not well explored. The neurocardiac axis theory and neurogenic stunned myocardium phenomenon could partly explain the brain-heart link and interactions and can thus pave the way to a better understanding and management of TBI. Several observational retrospective studies have shown a promising role for beta-adrenergic blockers in patients with TBI in reducing the overall TBI-related mortality. However, several questions remain to be answered in clinical randomized-controlled trials, including population selection, beta blocker type, dosage, timing, and duration of therapy, while maintaining the optimal mean arterial pressure and cerebral perfusion pressure in patients with TBI.
Recommended Citation
El-Menyar, A., Goyal, A., Latifi, R., Al-Thani, H., & Frishman, W. (2017). Brain-heart Interactions in Traumatic Brain Injury. Cardiology in Review, 25 (6), 279-288. https://doi.org/10.1097/CRD.0000000000000167
