NYMC Faculty Publications

Enhanced Depth Imaging Optical Coherence Tomography of Optic Nerve Head Drusen

Author Type(s)

Faculty

DOI

10.1016/j.ophtha.2012.12.035

Journal Title

Ophthalmology

First Page

1409

Last Page

1414

Document Type

Article

Publication Date

7-1-2013

Keywords

Adolescent, Adult, Aged, Cross-Sectional Studies, Female, Humans, Intraocular Pressure, Male, Middle Aged, Optic Disk, Optic Disk Drusen, Photography, Prospective Studies, Tomography, Optical Coherence, Ultrasonography, Visual Acuity, Visual Field Tests, Visual Fields, Young Adult

Disciplines

Medicine and Health Sciences

Abstract

OBJECTIVE: To assess the value of enhanced depth imaging optical coherence tomography (EDI OCT) in diagnosing and evaluating optic nerve head drusen (ONHD) compared with conventional diagnostic methods.

DESIGN: Prospective, comparative, cross-sectional study.

PARTICIPANTS: Thirty-four patients with clinically visible or suspected ONHD in either eye based on dilated optic disc examination or optic disc stereophotography and without ocular comorbidity.

METHODS: Spectral-domain OCT of the optic nerve head in both conventional (non-EDI) and EDI modes, ultrasound B-scan, and standard automated perimetry were performed on both eyes of all participants.

MAIN OUTCOME MEASURES: Detection and findings of ONHD between EDI OCT and conventional diagnostic methods.

RESULTS: Sixty-eight eyes were clinically classified into 3 groups: 32 eyes with definite ONHD, 25 eyes with suspected ONHD, and 11 normal-appearing fellow eyes. In the definite ONHD group, EDI OCT, non-EDI OCT, and ultrasound B-scan were positive for ONHD in all eyes and visual field (VF) was abnormal in 24 eyes. In the suspected ONHD group, EDI OCT, non-EDI OCT, ultrasound B-scan, and VF were positive in 17, 14, 7, and 3 eyes, respectively; 8 eyes had no evidence of ONHD in any of the tests. In normal-appearing fellow eyes, EDI OCT, non-EDI OCT, ultrasound B-scan, and VF were positive in 3, 1, 1, and 0 eyes, respectively; 4 eyes had no evidence of ONHD in any of the tests. Enhanced depth imaging OCT had a significantly higher ONHD detection rate than ultrasound B-scan in all eyes (52/68 eyes vs. 40/68 eyes; P

CONCLUSIONS: Enhanced depth imaging OCT detects lesions likely representing ONHD more often and better assesses their shape and structure than conventional tests.

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