NYMC Faculty Publications

Current Approach to Fertility Preservation by Embryo Cryopreservation

Author Type(s)

Faculty

DOI

10.1016/j.fertnstert.2013.03.020

Journal Title

Fertility and Sterility

First Page

1496

Last Page

1502

Document Type

Article

Publication Date

5-1-2013

Abstract

The ovaries are susceptible to damage following treatment with gonadotoxic chemotherapy, pelvic radiotherapy, and/or ovarian surgery. Gonadotoxic treatments have also been used in patients with various nonmalignant systemic diseases. Any women of reproductive age with a sufficiently high risk of developing future ovarian failure due to those medical interventions may benefit from embryo cryopreservation though the tools of assessment of such a risk are still not very precise. Furthermore, the risk assessment can be influenced by many other factors such as the delay expected after chemotherapy and the number of children desired in the future. Embryo cryopreservation is an established and most successful method of fertility preservation when there is sufficient time available to perform ovarian stimulation. This publication will review the current state, approach, and indications of embryo cryopreservation for fertility preservation.

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