NYMC Faculty Publications

Parafoveal Scotoma Progression in Glaucoma: Humphrey 10-2 Versus 24-2 Visual Field Analysis

Author Type(s)

Faculty

DOI

10.1016/j.ophtha.2013.01.045

Journal Title

Ophthalmology

First Page

1546

Last Page

1550

Document Type

Article

Publication Date

8-1-2013

Department

Ophthalmology

Keywords

Adult, Aged, Algorithms, Disease Progression, Exfoliation Syndrome, Female, Follow-Up Studies, Fovea Centralis, Glaucoma, Open-Angle, Humans, Intraocular Pressure, Male, Middle Aged, Retrospective Studies, Scotoma, Visual Field Tests, Visual Fields

Disciplines

Medicine and Health Sciences

Abstract

OBJECTIVE: To compare the performance of 10-2 versus 24-2 visual fields (VFs) in detecting progression of initial parafoveal scotoma (IPFS) in glaucomatous eyes.

DESIGN: Retrospective, observational study.

PARTICIPANTS: Glaucoma patients with the following criteria: (1) an IPFS (≥ 3 adjacent points with P

METHODS: Based on threshold map sensitivities, VF progression, defined as having 1 or more significantly progressing point(s) with a slope of sensitivity of less than -1.0 dB/year at P

MAIN OUTCOME MEASURES: The number of progressing eyes in 10-2 and 24-2 VF analyses.

RESULTS: Fifty eyes (50 patients) were included (mean age ± standard deviation, 62 ± 9 years). Mean follow-up period (5.7 vs. 5.6 years) and number of VFs (7.6 vs. 7.8) were similar between 10-2 and 24-2 analyses (all P>0.3). Significantly more progressing eyes were detected in 10-2 than in 24-2 analyses (24 vs. 11 eyes; P = 0.007). This difference became greater within the central 10° (24 vs. 4 eyes; P

CONCLUSIONS: The 10-2 VF detects more progressing eyes than the 24-2 VF in glaucoma patients with IPFS, suggesting that closer surveillance of the central VF using testing algorithms with closely spaced grids is warranted in eyes with parafoveal scotomas.

FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosure may be found after the references.

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