Hyper IgE Syndrome and Renal Cell Carcinoma

Authors

N Patel
Mark J. Ferretti, New York Medical College
John L. Phillips, New York Medical CollegeFollow

Journal Title

Case Reports in Urology

First Page

7083451

Document Type

Article

Publication Date

5-1-2017

Department

Urology

Abstract

Hyper IgE Syndrome (HIES) is an immunodeficiency disorder characterized by increased serum levels of IgE, eczema, and recurrent cutaneous and pulmonary infections. In this report, we present, to our knowledge, the first documented case of renal cell carcinoma (RCC) found in a patient with HIES. The patient received infectious disease clearance prior to obtaining a partial nephrectomy which revealed clear cell histology. Both HIES and RCC have an immunological basis for their pathophysiology and may involve common pathways. Further studies may provide insight into any possible link and clinicians should be mindful of immunocompromised patients who present with risk factors for genitourinary malignancy.

Recommended Citation

Patel, N., Ferretti, M., & Phillips, J. L. (2017). Hyper IgE Syndrome and Renal Cell Carcinoma. Case Reports in Urology, 2017, 7083451. https://doi.org/10.1155/2017/7083451

Publisher's Statement

Originally published in Case Reports in Urology, vol. 2017, Article ID 7083451, 3 pages. The original material can be found here.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.