Capsaicin is the active compound responsible for the pungency of hot chilli. Research has discovered its ability to desensitize peripheral nociceptive fibers which is useful in treating chronic pain disorders, specifically neuropathic pain syndromes. Capsaicin treatment comes in a variety of mediums including patches and creams and has been clinically proven to bring relief to patients with disorders such as post herpetic neuralgia, chronic regional pain syndrome and HIV related neuralgia. Exciting new forms of treatment are also in development and promise breakthroughs in the near future in this relatively young field of capsaicin-based analgesia.
Kornwasser, M. (2019). Capsacin and Analgesia. The Science Journal of the Lander College of Arts and Sciences, 12 (2). Retrieved from https://touroscholar.touro.edu/cgi/viewcontent.cgi?article=1215&context=sjlcas