Clostridia Botulinum (C. Botulinum) is a bacterium that produces a unique exotoxin, botulinum toxin (BTX). BTX induces flaccid muscle paralysis by inhibiting the release of acetylcholine at the cholinergic nerve endings. Recently, Botox, developed from BTX, has become a popular solution to reduce the appearance of hyper-functional facial rhytids. Facial wrinkles are caused by repetitive muscle contraction, and a treatment that directly addresses this will be effective. Injections of Botox temporarily relax or paralyze these muscles. This paper will briefly discuss the bacterial basis of Botox and its development. It will explain how the mechanism of action of BTX can be used therapeutically and cosmetically as well. The formula and development of Botox and similar drugs will be explained as well as the relevant facial anatomy. A detailed analysis of case studies and comparisons of different formulations are required before determining if Botox is an effective treatment. The side effects and risk factors involved will be assessed, concluding if Botox is a safe as well as effective treatment.
Eckstein, R. (2009). BOTOX and Its Effect on Wrinkles. The Science Journal of the Lander College of Arts and Sciences, 2(1), 70-83. Retrieved from https://touroscholar.touro.edu/sjlcas/vol2/iss1/7