The following is an excerpt from the article: Ischemia is defined as an inadequacy of blood flow to tissue. Ischemia can deprive tissue of oxygen and metabolic substrates and it can also prevent the removal of waste products. If the ischemia is maintained over enough time the tissue will lose its homeostasis and eventually die causing an infarct. Retinal ischemia occurs when the blood supply to the retina does not meet the metabolic needs that are required to sustain the retina. This can lead to retinal damage and severe vision loss. Ischemia is caused by occluded blood vessels.
Rube, J. (2010). Excitoxicity in Retinal Ischemia and Treatment Using Non-Competitive Receptor Antagonists. The Science Journal of the Lander College of Arts and Sciences, 3 (1). Retrieved from https://touroscholar.touro.edu/cgi/viewcontent.cgi?article=1177&context=sjlcas