Prognostic Value of Right Ventricular Systolic Pressure (RVSP) in Patients Hospitalized With Heart Failure

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Journal of the American College of Cardiology





Pulmonary hypertension in patients with heart failure has been established as a poor prognosis marker. There is little evidence studying the association between right ventricular systolic pressure (RVSP) used as a surrogate for pulmonary pressure and outcomes in heart failure patients.


A total of 972 patients admitted with heart failure in a single center were included in the present study. All patients were stratified based on their RVSP as ≤40 mm Hg or >40 mmHg. After comorbidities were matched using propensity scores, all-cause mortality, all-readmission, and cardiac readmission rates were analyzed between the two groups. Hazard ratio (HR) was used as an effect measure in our analysis. All analysis was carried out using STATA, version16.1.


We included 345 heart failure patients in each group after propensity score matching. Hospitalizations with RVSP >40 mm Hg were associated with higher rates of all-cause mortality compared with RVSP <40 mm Hg [HR: 1.60; 95% CI: 1.22-2.09; P-value <0.001]. Further, with all follow-up censored at 6 months RVSP >40 mm Hg were associated with higher rates of all-cause readmission [HR: 1.37; 95% CI: 1.09-1.73; P value =0.008], and cardiac readmission [HR: 1.41; 95% CI: 1.07-1.85; P value =0.014] compared with RVSP <40 mm Hg.


RVSP >40 mmHg in heart failure patients was independently associated with higher rates of all-cause mortality, all-cause readmission, and cardiac readmission.