NYMC Faculty Publications


Dermal Toxicity Biomarkers

Document Type

Book Chapter

Publication Date



Environmental Health Science


The identification and measurement of biomarkers, indicators of tissue, and cellular and subcellular responses to toxicants and environmental contaminants, has become an important field of research. It is critical to define biomarkers of toxicity for use as tools in epidemiological studies examining the complex interactions between toxicants and human health and to define appropriate interventional approaches. In this chapter, we discuss biomarkers of dermal toxicity, their origins, and the physiological events and processes they reflect. Markers that reflect specific stages of toxicant induced injury, and that reflect exposure, are contrasted. Specific dermal biochemical, histological, and ultrastructural biomarkers, and the classes they represent, are also discussed.

Publisher's Statement

Originally published in Biomarkers in Toxicology. https://doi.org/10.1016/B978-0-12-404630-6.00018-X