Author ORCID Identifier
OBJECTIVE: To assess change in overactive bladder (OAB) symptoms up to 5 years after surgery and to identify associated predictors of change from baseline.
METHODS: This is a secondary analysis of data from three multicenter urinary incontinence (UI) surgical trials of women with stress-predominant mixed UI assigned to Burch colposuspension, autologous fascial sling, or retropubic or transobturator midurethral slings. The primary outcome was improvement of 70% or greater from baseline in symptoms measured by the Urinary Distress Inventory-Irritative subscale. Surgical groups were compared within respective trials. Generalized linear models were fit using 1-year and up to 5-year data.
RESULTS: Significant improvements in UDI-I scores were reported by each surgical group one year after surgery (p
CONCLUSION: Most women with stress-predominant mixed UI experienced significant improvement in OAB symptoms after incontinence surgery although this initial improvement diminished over time. Obesity blunted symptom improvement.
LEVEL OF EVIDENCE: II.
Zyczynski, H., Albo, M., Goldman, H., Wai, C., Sirls, L., Brubaker, L., Norton, P., Varner, R., Carmel, M., & Kim, H. (2015). Change in Overactive Bladder Symptoms After Surgery for Stress Urinary Incontinence in Women. Obstetrics and Gynecology, 126 (2), 423-430. https://doi.org/10.1097/AOG.0000000000000929
This is the accepted manuscript version of this article. The publisher's final edited version of this article is available at https://doi.org/10.1097/AOG.0000000000000929