Tetrasomy 8 Associated with a Poor Prognosis in Acute Monoblastic Leukemia: A Case Report
We report a case of a 47-year-old male from West Africa who presented with sepsis and was found to have acute monoblastic leukemia associated with tetrasomy 8 detected on bone marrow samples. This was the only chromosomal abnormality found. Tetrasomy 8 is a rare genetic finding that has been reported in acute myeloid leukemia (AML), predominantly the monocytic lineage. It carries a poor prognosis with a high mortality rate.
Farag, F., Morcus, R., Ramachandran, P., Josan, K., & Wang, J. (2019). Tetrasomy 8 Associated with a Poor Prognosis in Acute Monoblastic Leukemia: A Case Report. Cureus, 11 (2), 4068-4068. https://doi.org/10.7759/cureus.4068