High Flow From Impella 5.5 With Partial Veno-Arterial Extracorporeal Membrane Oxygenation Support: Case Series
Optimal flow balance between Impella 5.5 and veno-arterial extracorporeal membrane oxygenation (ECMO) support in the setting of EC-PELLA (ECMO+Impella) is unknown. Outcomes of high Impella 5.5 flow in the setting of EC-PELLA support were reviewed (N = 7). EC-PELLA was successfully explanted in 6 patients (bridge-to-transplant, N = 1; bridge-to-recovery, N = 5). The median duration of EC-PELLA support in explanted patients was 6 days. Survival at discharge was 71.4% (5 patients). In terms of device-related events, either VA-ECMO or Impella-related complications were not experienced. The median performance level of Impella 5.5 was P5 at the time of starting EC-PELLA support and then increased with time up to the median of P8 with increment of the Impella flow, and index (L/min/m ). The percentage of Impella flow per total EC- PELLA flow reached 50% after 48 h of support. The vasoactive-inotropic score and serum lactate level improved after institution of EC-PELLA support as well as the pulmonary artery pressures and central venous pressure. In conclusion, a high pump flow from Impella 5.5 with partial VA-ECMO support in the setting of EC-PELLA provided great support with favorable survival and device-related complications rate.
Ohira, S., Pan, S., Levine, A., Haidry, S. A., Aggawal-Gupta, C., Lanier, G., Gass, A., De La Pena, C., Goldberg, J. B., Spielvogel, D., & Kai, M. (2022). High Flow From Impella 5.5 With Partial Veno-Arterial Extracorporeal Membrane Oxygenation Support: Case Series. https://doi.org/10.1111/aor.14183