Α-Ketoglutaramate-A Key Metabolite Contributing to Glutamine Addiction in Cancer Cells

Authors

Arthur J. Cooper, Department of Biochemistry and Molecular Biology, New York Medical College, Valhalla, NY, United States.Follow
Thambi Dorai, Department of Biochemistry and Molecular Biology, New York Medical College, Valhalla, NY, United States.
John T. Pinto, Department of Biochemistry and Molecular Biology, New York Medical College, Valhalla, NY, United States.Follow
Travis T. Denton, Department Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Washington State University Health Sciences Spokane, Spokane, WA, United States.

Author Type(s)

Faculty

DOI

10.3389/fmed.2022.1035335

Journal Title

Frontiers in Medicine

First Page

1035335

Document Type

Article

Publication Date

1-1-2022

Department

Biochemistry and Molecular Biology

Keywords

glutaminase II pathway, glutamine transaminase K, glutamine transaminases, methionine salvage pathway, nitrogen homeostasis, α-ketoglutaramate, α-ketoglutarate, ω-amidase

Disciplines

Medicine and Health Sciences

Recommended Citation

Cooper, A. J., Dorai, T., Pinto, J. T., & Denton, T. T. (2022). Α-Ketoglutaramate-A Key Metabolite Contributing to Glutamine Addiction in Cancer Cells. Frontiers in Medicine, 13, 1035335. https://doi.org/10.3389/fmed.2022.1035335