NYMC Faculty Publications

Arterial Length as a Predictor for Glaucoma Status

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Investigative Ophthalmology & Visual Science

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Purpose : Using primary arterial lengths as an indicator of overall macular fibers. We hypothesize that the arterial lengths delineate the macular area. With decrease in macular fibers there would be less binding and expected expansion of the major arterioles of the superotemporal (ST) and inferotemporal (IT).

Methods : Arteriolar lengths were measured in a standardized system from first branching at the optic nerve to the first bifurcation. Comparison was made between Normal (N=25) vs the given open angle glaucoma states of: mild (N=47), moderate (N=49), severe (N=43). A ratio was carried out between Normal to given disease state, Student T-Test carried out for comparison.

Results : Glaucoma Categories show a difference from normal arterial lengths. There is a lengthening of the arterial segment.

Conclusions : With the lengthening of the arterial segment relative to glaucomatous status, it is sensed that this purports to widening of the macular arcades due to decreased anchoring from the nerve fiber layer as it relates to glaucoma, ie, with more glaucomatous change there is a resultant decrease in NFL. More development and testing will be needed to develop such algorithms.