NYMC Faculty Publications

2D Accordion-Like Mxene Nanosheets as a Sensitive Electrode Material for Baicalin Sensing

Author Type(s)

Faculty

DOI

10.1002/elan.202060535

Journal Title

Electroanalysis

First Page

1308

Last Page

1314

Document Type

Article

Publication Date

5-2021

Department

Pathology, Microbiology and Immunology

Abstract

Herein, accordion-like MXene nanosheets was used as electrode sensing material for baicalin determination in traditional Chinese medicine preparation for the first time. The consecutive multilayer nanostructure of MXene observably enhanced the electroactive surface area of electrode and accelerated the electron transfer rate to acquire outstanding electrochemical response to baicalin. The electrode process of baicalin and relative dynamic parameters were investigated using cyclic voltammetry and chronocoulometry. Under optimized conditions, a good linear relationship was achieved between the response current and baicalin levels over the range of 0.08–60 μM with a detection limit of 26 nM (S/N=3). The developed sensor was successfully applied for baicalin monitoring in traditional Chinese medicine preparation and human urine samples.

Share

COinS