Evidence-Based Management of Arrhythmogenic Right Ventricular Cardiomyopathy in Pregnancy
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetic disorder resulting in fibrofatty replacement of the myocardium. Genetic mutations in genes encoding for desmosome proteins result in a ventricular myocardium prone to arrhythmias and heart failure. Although ARVC is known for a few decades, most of the outcomes in pregnancy are reported recently. Pregnancy leads to significant physiological changes with excess mechanical stress on the myocardium. All the retrospective studies suggest that pregnancy is well tolerated in these patients despite the high risk of arrhythmias and heart failure. Our review focuses on the most up-to-date evidence on the management of ARVC patients during the antepartum and postpartum period.
Khosla, J., Golamari, R., Cai, A., Benson, J., Aronow, W. S., Jain, R., & Jain, R. (2021). Evidence-Based Management of Arrhythmogenic Right Ventricular Cardiomyopathy in Pregnancy. Future Cardiology, 17 (4), 693-703. https://doi.org/10.2217/fca-2020-0127