Clinical Significance of a False Positive Glucose Challenge Test in Patients with a High Body Mass Index
Obstetrics and Gynecology
OBJECTIVE: To determine if there is an increased maternal or neonatal morbidity in overweight and obese patients with a false positive glucose challenge test (GCT). METHODS: Patients with a body mass index (BMI) >/=25.0 at registration were included in this prospective 36-month study. The study cohort consisted of patients with a false positive (FP) GCT, with two comparison cohorts: those with a (1) screen negative (SN) GCT result and (2) true positive (TP) GCT result. Risks were reported as odd ratios with 95% confidence intervals, with a P/=4000 g in the FP cohort, but this fell short of reaching statistical significance. When comparing the FP to TP cohorts, rates of gestational hypertension, pre-eclampsia, and infants >/=4000 g were similar; however, neonatal morbidity was increased in the TP group. CONCLUSIONS: Overweight and obese patients with a FP glucose challenge screen are more likely to have adverse maternal outcomes. Neonatal morbidity was not increased.
Borja, A., Moretti, M., & Lakhi, N. (2017). Clinical Significance of a False Positive Glucose Challenge Test in Patients with a High Body Mass Index. Journal of Perinatal Medicine, 45 (3), 383-389. https://doi.org/10.1515/jpm-2016-0161