NYMC Faculty Publications
IncobotulinumtoxinA in Clinical Literature
Author Type(s)
Faculty
DOI
10.1177/1090820X12474635
Journal Title
Aesthetic Surgery Journal
First Page
23
Last Page
23
Document Type
Article
Publication Date
3-1-2013
Department
Otolaryngology
Abstract
IncobotulinumtoxinA is the third neurotoxin type A to be approved for aesthetic use in the United States. Because incobotulinumtoxinA has been in use in Europe for some time, the clinical literature is fairly replete with references to its properties and characteristics, as well as its safety and efficacy. In North America, 2 pivotal trials, referred to as GL-1 and GL-2, investigated the safety and efficacy of incobotulinumtoxinA in the glabellar region; both are currently in press with another journal. Other published studies of incobotulinumtoxinA are also described in depth in this article, including reports on aesthetic indications, diffusion, therapeutic indications, and studies pertaining to the preclinical and clinical pharmacology of incobotulinumtoxinA. Topics addressed include potency variability, mean concentration, stability and dissociation, and endopeptide immunoassay.
Recommended Citation
Lorenc, Z., Kenkel, J., Fagien, S., Hirmand, H., Nestor, M., Sclafani, A., Sykes, J., & Waldorf, H. (2013). IncobotulinumtoxinA in Clinical Literature. Aesthetic Surgery Journal, 33 (1 Suppl), 23-23. https://doi.org/10.1177/1090820X12474635
