NYMC Faculty Publications

Risk Factors for Intrapartum Fever in Term Gestations and Associated Maternal and Neonatal Sequelae

Journal Title

Gynecologic and Obstetric Investigation

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Document Type


Publication Date

January 2017


Obstetrics and Gynecology


AIM: To determine factors associated with intrapartum fever and to examine associated maternal and neonatal outcomes. METHODS: Retrospective study of patients between 360/7 and 420/7 gestational weeks who entered spontaneous or induced active labor and developed temperature >=38 degrees C; a similar group that did not develop fever were controls. Univariate and multivariate analyses were performed with p /=720 min (OR 3.59, 95% CI 1.97-6.55, p /=120 min (OR 4.76, 95% CI 2.29-9.89, p /=240 min (46.4 vs. 79.6%, p<0.001), increasing number of vaginal exams (4 vs. 6, p<0.001), oxytocin (44.8 vs. 63.0%, p = 0.014), and meperidine (14.7 vs. 35.2%, p<0.001) were all associated with intrapartum fever. Associated morbidity included cesarean delivery (22.5 vs. 44.4%, p = 0.001), Apgar score <7 at 5 min (0.7 vs. 5.6%, p = 0.011), and neonatal intensive care unit admission (9.5 vs. 51.9%, p<0.001). CONCLUSION: We have identified several noninfectious factors that are associated with intrapartum fever. Modification of risk factors may improve both maternal and neonatal outcomes.