BACKGROUND: We present a case of gamma-delta T-cell lymphoma that does not fit the current World Health Organization classifications. CASE PRESENTATION: A 74-year-old Caribbean-American woman presented with lymphocytosis, pruritus, and non-drenching night sweats. Bone marrow and peripheral blood analyses both confirmed the diagnosis of gamma-delta T-cell lymphoma. An axillary lymph node biopsy was negative for lymphoma. Clinically absent hepatosplenomegaly and skin lesions with biopsy-proven gamma-delta T-cell lymphoma suggest that she is unclassifiable within the current classification system. CONCLUSIONS: We believe this is a case of not otherwise specified gamma-delta T-cell lymphoma. Accumulation of these rare not otherwise specified cases will be important for future classification which further defines the biology of this disease.
Sindhu, H., Chen, R., Chen, H., Wong, J., Chaudhry, R., Xu, Y., & Wang, J. (2017). Gamma-Delta (gammadelta) (γδ) T-cell Lymphoma - Another Case Unclassifiable by World Health Organization Classification: a Case Report. Journal of Medical Case Reports, 11 (1), 163. https://doi.org/10.1186/s13256-017-1312-5
Originally published in Journal of Medical Case Reports (2017) 11:163. The original material can be found here.
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