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The Science Journal of the Lander College of Arts and Sciences

Authors

Ellie Wolff

Abstract

This paper investigates the relationship between key health demographics and COVID-19 mortality while focusing on identifying both physiological and genetic factors that contribute to variations in mortality rates. Specifically, it examines how pre-existing conditions—such as sex, autoimmune disorders, cardiovascular diseases, and obesity—interact with COVID-19 pathophysiology to influence patient outcomes. While previous research has highlighted demographic disparities in hospital mortality rates, this study aims to establish a causal, mechanistic link between these health factors and COVID-19 severity. Methods to extract and analyze data included literature review using existing studies such as peer-reviewed articles and reports from PubMed, CDC, etc. By analyzing the biological and clinical impacts of these variables, the paper provides a more comprehensive understanding of the determinants of COVID-19 mortality and highlights the need for continued research to better inform public health strategies and clinical care.

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