The Science Journal of the Lander College of Arts and Sciences
Abstract
The global shortage of transplantable organs represents a critical medical challenge, with current organ donation systems meeting less than 10% of the worldwide need. This situation has spurred intensive research into regenerative medicine, particularly focusing on the potential of generating organs from a patient’s own stem cells. This review examines the current state of stem cell research and its applications in organ generation, analyzing both the progress made and the challenges that remain. Through a comprehensive analysis of recent literature and clinical trials, the study explores the fundamental principles of stem cell biology, current therapeutic applications, and the role of supporting technologies such as bioscaffolding and organoid development. The findings indicate significant advances in stem cell manipulation and tissue engineering, particularly in areas such as insulin-producing beta cells and cardiac tissue repair. However, substantial challenges persist, including organ structural complexity, functional integration, and potential tumorigenesis. While complete organ generation remains elusive, incremental successes in stem cell applications suggest a promising trajectory toward this goal. This review concludes that while current technology cannot yet generate fully functional organs, continued research advances and investment in this field may eventually transform transplantation medicine.
Recommended Citation
David Heimowitz. (2025). Can Organs Be Generated from a Patient’s Own Stem Cells?. The Science Journal of the Lander College of Arts and Sciences, 18(2), 100-105. Retrieved from https://touroscholar.touro.edu/sjlcas/vol18/iss2/13
