•  
  •  
 

The Science Journal of the Lander College of Arts and Sciences

Abstract

Pancreatic cancer is one of the worst forms of cancer that can develop in an individual. Traditionally, chemotherapy is administered but it has very limited success. Using the immune system to treat the cancer is very enticing and many studies have been conducted to attempt to harness the body’s own mechanisms to defeat the cancer. It seems that in order to properly treat the tumor a two pronged approach must be used. First, the immune system must be stimulated to react to the tumor and attack it. A possible cytokine that can be utilized is interferon alpha, which could result in a proliferation of T cells, but also appears to cause severe side effects. This can be overcome by introducing the interferon virally. Second, immune suppression must be overcome. This can be accomplished by using antibodies to destroy regulatory (CD-25) T cells that would ordinarily prevent a T cell response. However, care must be taken to avoid inducing autoimmunity.

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.