Euphoria from Drinking Alcoholic Beverages May Be Due to Reversible Constriction of Cerebral Blood Vessels: Potential Roles of Unrecognized Ionized Hypomagnesemia, and Release of Ceramides and Platelet-Activating Factor
The authors discuss the feeling of euphoria when drinking alcohol. They summarize studies that suggest this feeling is due to blood vessel constriction, and explain why they believe that the specific mechanism that results in euphoria is the rapid, reversible release o free magnesium ions ([Mg2+]) coupled to the release of ceramides and platelet-activating factor (PAF).
Altura, B. M., Zhang, A., Shah, N. C., Shah, G. J., Gebrewold, A., & Altura, B. T. (2016). Euphoria from drinking alcoholic beverages may be due to reversible constriction of cerebral blood vessels: Potential roles of unrecognized ionized hypomagnesemia, and release of ceramides and platelet-activating factor. Clinical Research Trials, 2(6), 242-245.