Author ORCID Identifier
The use of complementary and alternative medicine (CAM) is gaining popularity in the Western world. Among the general public, CAM is often perceived to be associated with less stigma, fewer adverse effects, and may be more affordable. A number of patients utilize CAM for the treatment of depression; however, as there is limited scientific evidence, the safety profile of these supplements are largely unknown. In this case, a 42-year-old man developed hypomania approximately 1 week after S-adenosylmethionine (SAMe) and 5-hydroxytryptophan (5-HTP) therapy was initiated for depression. The combination of SAMe and 5-HTP can potentially induce hypomanic episodes.
Olsufka, W., & Abraham, M. (2017). Treatment-Emergent Hypomania Possibly Associated with Over-the-Counter Supplements. Mental Health Clinician, 7 (4), 160-163. https://doi.org/10.9740/mhc.2017.07.160
Originally published in Mental Health Clinician, 7(4), 160-163. The original material can be found here.
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial 3.0 License