Exploring the Effects of Intrastriatal AAV5-miHTT-Lowering Therapy on Transcriptional Dysregulation, MRS Signal, and Mutant Huntingtin Levels in the Q175FDN Mouse Model of Huntington's Disease

Authors

Blair Leavitt
Anouk Stam
Cynthia Brouwers
Terri Petkau
Michael Vermeulen
Andrew Yung
Bretta Russell-Schulz
Piotr Kozlowski, Touro College
Alex Mackay
Da Ma
Faisal Beg
Sara Mostafavi
Sander van Deventer
Melvin M. Evers
Pavlina Konstantinova
Astrid Valles

Publication Date

12-18-2020

DOI

10.1007/S13311-020-00945-Z

ISSN

1933-7213

Publication Title

Neurotherapeutics

Recommended Citation

Leavitt, B., Stam, A., Brouwers, C., Petkau, T., Vermeulen, M., Yung, A., Russell-Schulz, B., Kozlowski, P., Mackay, A., Ma, D., Beg, F., Mostafavi, S., van Deventer, S., Evers, M. M., Konstantinova, P., & Valles, A. (2020). Exploring the Effects of Intrastriatal AAV5-miHTT-Lowering Therapy on Transcriptional Dysregulation, MRS Signal, and Mutant Huntingtin Levels in the Q175FDN Mouse Model of Huntington’s Disease. Neurotherapeutics, 17(SUPPL 1), S20. https://doi.org/10.1007/s13311-020-00945-z