'Turning up the Heat': Noninvasive Thermal Evaluation for Patient Selection and Assessing Clinical Outcomes Following Geniculate Artery Embolization

Author Type(s)

Faculty, Resident/Fellow

Document Type

Abstract

Publication Date

2022

DOI

10.1007/s00270-022-03246-4

Journal Title

CardioVascular and Interventional Radiology

Department

Radiology

Abstract

Learning Objectives: -Discuss the pathophysiology of osteoarthritis as it relates to locoregional temperature variation. -To describe noninvasive thermal evaluation/thermography for patient selection and assessing clinical outcomes following geniculate artery embolization (GAE). -Provide an overview of the therapeutic role of GAE for the treatment of pain associated with osteoarthritis. Background: Osteoarthritis is the predominate degenerative joint disease and prevalent cause of chronic disability. The pathogenesis is thought to be synovial inflammation resulting in proinflammatory mediators release, angiogenesis, as well as local tissue destruction. Sensory neural network recruitment is presumably responsible for pain. GAE has been shown to be an effective treatment for pain associated with mild to moderate osteoarthritis refractory to conservative treatment. Traditionally, the selection of patient for GAE has largely been based on physical examination and imaging. We postulated that a) local hyperemia may cause temperature elevation, which may be of diagnostic value and b) temperature decreases after GAE may be indicator of the procedure efficiency. Clinical Findings/Procedure Details: 1. Review of pathophysiology of osteoarthritis as it relates to locoregional thermoregulatory characteristics. 2. Overview of available tools for locoregional thermal assessment a) Pre- and post-procedural local dermal temperature measurements with Infrared thermometer for both the ipsilateral and contralateral knees b) Pre- and post-procedural thermography correlating to patient symptomology. 3. Discuss potential limitations and pitfalls. Conclusion: Noninvasive thermal evaluation of the knee may play a significant role in the patient selection and assessment of clinical outcomes following geniculate artery embolization. However, more research is necessary before widespread utilization.

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