Exosomes, Microvesicles, and Other Extracellular Vesicles-a Keystone Symposia Report

Author Type(s)

Faculty

Document Type

Abstract

Publication Date

5-2023

DOI

10.1111/nyas.14974

Journal Title

Annals of the New York Academy of Sciences

Department

Pathology, Microbiology and Immunology

Abstract

Extracellular vesicles (EVs) are small, lipid-bilayer-bound particles released by cells that can contain important bioactive molecules, including lipids, RNAs, and proteins. Once released in the extracellular environment, EVs can act as messengers locally as well as to distant tissues to coordinate tissue homeostasis and systemic responses. There is a growing interest in not only understanding the physiology of EVs as signaling particles but also leveraging them as minimally invasive diagnostic and prognostic biomarkers (e.g., they can be found in biofluids) and drug-delivery vehicles. On October 30-November 2, 2022, researchers in the EV field convened for the Keystone symposium "Exosomes, Microvesicles, and Other Extracellular Vesicles" to discuss developing standardized language and methodology, new data on the basic biology of EVs and potential clinical utility, as well as novel technologies to isolate and characterize EVs.

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Please see the work itself for a complete list of authors.

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