NYMC Faculty Publications
DOI
10.18632/oncotarget.23601
Journal Title
Oncotarget
First Page
6623
Last Page
6629
Document Type
Article
Publication Date
12-1-2017
Department
Pediatrics
Keywords
Influenza B virus, Influenza Vaccines Israel, Viral Vaccines
Disciplines
Medicine and Health Sciences
Abstract
While infection with influenza A viruses has been extensively investigated, infections with influenza B viruses which are commonly categorized into the highly homologous Victoria and Yamagata lineages, are less studied, despite their considerable virulence. Here we used RT-PCR assays, hemagglutination inhibition assays and antibody titers to determine the levels of influenza B infection. We report of high influenza B Victoria virus prevalence in the 2015-16 winter season in Israel, affecting approximately half of the Israeli population. We further show that the Victoria B virus infected individuals of all ages and that it was present in the country throughout the entire winter season. The vaccine however included the inappropriate Yamagata virus. We propose that a quadrivalent vaccine, that includes both Yamagata and Victoria lineages, should be considered for future influenza vaccination.
Recommended Citation
Sharabi, S., Bassal, R., Friedman, N., Drori, Y., Alter, H., Glatman-Freedman, A., Hindiyeh, M., Cohen, D., Mendelson, E., Shohat, T., & Mandelboim, M. (2017). Forty Five Percent of the Israeli Population were Infected with the Influenza B Victoria virus During the Winter season 2015-16. Oncotarget, 9 (5), 6623-6629. https://doi.org/10.18632/oncotarget.23601
