NYMC Faculty Publications
Amiodarone Induced Myxedema Coma: Two Case Reports and Literature Review
DOI
10.1016/j.hrtlng.2018.03.012
Journal Title
Heart & Lung
First Page
429
Last Page
431
Document Type
Article
Publication Date
1-1-2018
Department
Medicine
Abstract
Amiodarone is a benzofuran derivative that contains 37% iodine by weight and is structurally similar to the thyroid hormones. Amiodarone has a complex effect on the thyroid gland, ranging from abnormalities of thyroid function tests to overt thyroid dysfunction, with either thyrotoxicosis or hypothyroidism. Myxedema coma secondary to amiodarone use has been rarely reported in the literature. Our two case reports are an add on to the literature, and illustrate that amiodarone is an important cause of thyroid dysfunction including hypothyroidism and myxedema coma. Hence, healthcare providers should have a high index of suspicion for these conditions while treating patients who are taking amiodarone therapy as early recognition and management are essential to optimize outcomes.
Recommended Citation
Hawatmeh, A., Thawabi, M., Abuarqoub, A., & Shamoon, F. (2018). Amiodarone Induced Myxedema Coma: Two Case Reports and Literature Review. Heart & Lung, 47 (4), 429-431. https://doi.org/10.1016/j.hrtlng.2018.03.012
