Systolic Blood Pressure and Outcomes in Patients With Heart Failure With Preserved Ejection Fraction

Authors

Apostolos Tsimploulis
Phillip H. Lam
Cherinne ArundelFollow
Steven N. Singh
Charity J. Morgan
Charles Faselis
Prakash Deedwania
Javed Butler
Wilbert S. Aronow, New York Medical CollegeFollow
Clyde W. Yancy
Gregg C. Fonarow
Ali AhmedFollow

DOI

10.1001/jamacardio.2017.5365

Journal Title

JAMA Cardiology

First Page

288

Last Page

297

Document Type

Article

Publication Date

4-1-2018

Department

Medicine

Abstract

Importance: Lower systolic blood pressure (SBP) levels are associated with poor outcomes in patients with heart failure. Less is known about this association in heart failure with preserved ejection fraction (HFpEF). Objective: To determine the associations of SBP levels with mortality and other outcomes in HFpEF. Design, Setting, and Participants: A propensity score-matched observational study of the Medicare-linked Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF) registry included 25354 patients who were discharged alive; 8873 (35.0%) had an ejection fraction of at least 50%, and of these, 3915 (44.1%) had stable SBP levels (

Recommended Citation

Tsimploulis, A., Lam, P., Arundel, C., Singh, S., Morgan, C., Faselis, C., Deedwania, P., Butler, J., Aronow, W., Yancy, C., Fonarow, G., & Ahmed, A. (2018). Systolic Blood Pressure and Outcomes in Patients With Heart Failure With Preserved Ejection Fraction. JAMA Cardiology, 3 (4), 288-297. https://doi.org/10.1001/jamacardio.2017.5365