NYMC Faculty Publications

Tuberculin-Active Carbohydrate That Induces Inhibition of Macrophage Migration but Not Lymphocyte Transformation

Journal Title

Science (New York, N.Y.)

First Page

637

Last Page

639

Document Type

Article

Publication Date

November 1970

Department

Pathology, Microbiology and Immunology

Abstract

A tuberculin carbohydrate fraction, GAE, in sensitized animals induced a delayed type of skin reactivity and inhibited the migration of macrophages but failed to stimulate lymphocyte transformation in vitro. Tuberculin protein-containing fractions were active in each test. These results show that in vitro lymphocyte transformation is not necessarily a corollary of delayed type hypersensitivity.

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