NYMC Faculty Publications
DOI
10.1016/j.rmcr.2017.08.003
Journal Title
Respiratory Medicine Case Reports
First Page
150
Last Page
153
Document Type
Article
Publication Date
8-6-2017
Department
Medicine
Abstract
Small and non-small cell lung cancer present in a variety of radiologic and clinical patterns, and have been linked to smoking. Primary adenocarcinoma of the lung has been increasingly recognized in females and nonsmokers, often presenting a diagnostic challenge. In the absence of smoking history, these radiographic patterns may be initially misdiagnosed as an infectious or inflammatory condition, often delaying the diagnosis of malignancy. We report two cases of female patients with relatively short or no smoking history presenting with diffuse pulmonary infiltrates not typically seen in primary lung cancer, which created a diagnostic challenge, ultimately diagnosed as primary lung adenocarcinoma. Each case had different subtype patterns of adenocarcinoma. The first case described adenocarcinoma of mostly acinar pattern; while the second case was noted to have adenocarcinoma of micropapillary pattern. Given lung adenocarcinoma's nonspecific presentation, which may mimic infectious and diffuse interstitial lung disease, the above cases highlight the importance of entertaining lung adenocarcinoma as part of the differential diagnosis of such presentations.
Recommended Citation
Ismail, M., & Sekhon, R. (2017). Diffuse Pulmonary Infiltrates: a Guise of Adenocarcinoma. Respiratory Medicine Case Reports, 22, 150-153. https://doi.org/10.1016/j.rmcr.2017.08.003
Publisher's Statement
Originally published in Respiratory Medicine Case Reports, 13, 600-607. Licensed under CC-BY-NC-ND 4.0. The original material can be found here.
Included in
Analytical, Diagnostic and Therapeutic Techniques and Equipment Commons, Neoplasms Commons, Respiratory Tract Diseases Commons