NYMC Faculty Publications

Advances in Cellular and Humoral Immunotherapy - Implications for the Treatment of Poor Risk Childhood, Adolescent, and Young Adult B-Cell Non-Hodgkin Lymphoma

Journal Title

British Journal of Haematology

First Page

1055

Last Page

1070

Document Type

Article

Publication Date

June 2019

Department

Pediatrics

Abstract

Patients with relapsed, refractory or advanced stage B non-Hodgkin lymphoma (NHL) continue to have a dismal prognosis. This review summarises current and novel cellular and immunotherapy for these high-risk populations, including haematopoietic stem cell transplant, bispecific antibodies, viral-derived cytotoxic T cells, chimeric antigen receptor (CAR) T cells, and natural killer (NK) cell therapy, as discussed at the 6th International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin Lymphoma on September 26th-29th 2018 in Rotterdam, the Netherlands, and explores the future of NK/CAR NK therapies.

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