NYMC Faculty Publications
Cardiac Manifestations in Idiopathic Inflammatory Myopathies: An Overview
DOI
10.1097/CRD.0000000000000241
Journal Title
Cardiology in Review
First Page
131
Last Page
137
Document Type
Article
Publication Date
May 2019
Department
Medicine
Abstract
Idiopathic inflammatory myopathies are a group of autoimmune diseases that are characterized by muscle inflammation resulting in elevated muscle enzyme release and distinctive biopsy findings. This group of conditions includes polymyositis, dermatomyositis, inclusion body myositis, and necrotizing autoimmune myopathy. Although they have many similarities, the inflammatory myopathies differ in their clinical, pathological, and treatment realms. Extramuscular manifestations may involve many organs that include the skin, joints, heart, lungs, and gastrointestinal tract. Cardiovascular involvement is one of the leading causes of mortality in polymyositis and dermatomyositis. Surveillance and prevention of cardiovascular risk factors are therefore essential. In this article, we review the epidemiology, pathophysiology, clinical manifestations, diagnosis, and management of cardiovascular complications of idiopathic inflammatory myopathies with the main focus on polymyositis and dermatomyositis.
Recommended Citation
Jayakumar, D., Zhang, R., Wasserman, A., & Ash, J. (2019). Cardiac Manifestations in Idiopathic Inflammatory Myopathies: An Overview. Cardiology in Review, 27 (3), 131-137. https://doi.org/10.1097/CRD.0000000000000241