NYMC Faculty Publications
The Relevance of Serum Albumin Among Elderly Patients With Acute Decompensated Heart Failure
DOI
10.11909/j.issn.1671-5411.2019.07.005
Journal Title
Journal of Geriatric Cardiology
First Page
522
Last Page
528
Document Type
Article
Publication Date
July 2019
Department
Medicine
Abstract
Objective: To assess the prognostic utility of serum albumin among elderly patients admitted for acute decompensated heart failure (ADHF) in terms of all-cause mortality and also to identify the predictors of hypoalbuminemia. Methods: Retrospective cohort study of 119 elderly patients admitted for ADHF. Elderly patients were defined as patients over the age of 65 years. The patients were followed up for approximately 11 years. Patients with advanced renal failure, liver disease not due to HF, cancer and other causes of low life expectancy were excluded. Hypoalbuminemia was defined as serum albumin = 2.9 g/dL. Results: The study was made up of 65 females and 54 males with age ranging from 65 to 96 years. Of the 119 elderly patients with ADHF, there were 26 deaths. A significantly higher proportion of patients in the mortality group had an admission serum albumin level of = 2.9 g/dL than those surviving (P = 0.011). After Cox's logistic regression, low albumin (P = 0.016), elevated direct bilirubin (P = 0.03), age greater than 85 (P = 0.008), lack of use of beta blockers (P = 0.0001) and left ventricular ejection fraction less than 35% (P = 0.005) increased the risk of death. Elevated serum creatinine (P = 0.0357) was the only predictor of hypoalbuminemia following multiple linear regression. Conclusions: Hypoalbuminemia may be an unrecognized marker of death in elderly patients with ADHF.
Recommended Citation
Mene-Afejuku, T. O., Moisa, E., Akinlonu, A., Dumancas, C., Veranyan, S., Perez, J., Salazar, P., Chaudhari, S., Pekler, G., Mushiyev, S., & Visco, F. (2019). The Relevance of Serum Albumin Among Elderly Patients With Acute Decompensated Heart Failure. Journal of Geriatric Cardiology, 16 (7), 522-528. https://doi.org/10.11909/j.issn.1671-5411.2019.07.005