NYMC Faculty Publications

Surveillance Imaging in Pediatric Lymphoma

DOI

10.1007/s00247-019-04511-4

Journal Title

Pediatric Radiology

First Page

1565

Last Page

1573

Document Type

Article

Publication Date

October 2019

Department

Pediatrics

Keywords

Children, Computed tomography, Hodgkin lymphoma, Late effects, Non-Hodgkin lymphoma, Positron emission tomography, Response-based surveillance, Risk-adapted surveillance, Surveillance imaging

Disciplines

Medicine and Health Sciences

Abstract

Current therapies used in treating children with Hodgkin lymphoma and many histological subtypes of non-Hodgkin lymphoma have resulted in overall survival rates exceeding 90% in many instances. With increasing concerns related to the cost of radiologic imaging, exposure to ionizing radiation, and potential false-positive results, the role of routine off-therapy surveillance imaging has been called into question. Although radiologic imaging plays an important role in diagnosing and assessing treatment response, in these children - the majority of whom have an excellent outcome following completion of therapy - there is an opportunity to dramatically reduce the number of off-therapy imaging evaluations. This review summarizes several recent studies in both Hodgkin and non-Hodgkin lymphoma providing evidence to support these efforts. In addition, we propose a surveillance imaging strategy that uses a novel risk-adapted and response-based approach to determine which children would most benefit from off-therapy imaging surveillance.

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