NYMC Faculty Publications
Surveillance Imaging in Pediatric Lymphoma
DOI
10.1007/s00247-019-04511-4
Journal Title
Pediatric Radiology
First Page
1565
Last Page
1573
Document Type
Article
Publication Date
October 2019
Department
Pediatrics
Keywords
Children, Computed tomography, Hodgkin lymphoma, Late effects, Non-Hodgkin lymphoma, Positron emission tomography, Response-based surveillance, Risk-adapted surveillance, Surveillance imaging
Disciplines
Medicine and Health Sciences
Abstract
Current therapies used in treating children with Hodgkin lymphoma and many histological subtypes of non-Hodgkin lymphoma have resulted in overall survival rates exceeding 90% in many instances. With increasing concerns related to the cost of radiologic imaging, exposure to ionizing radiation, and potential false-positive results, the role of routine off-therapy surveillance imaging has been called into question. Although radiologic imaging plays an important role in diagnosing and assessing treatment response, in these children - the majority of whom have an excellent outcome following completion of therapy - there is an opportunity to dramatically reduce the number of off-therapy imaging evaluations. This review summarizes several recent studies in both Hodgkin and non-Hodgkin lymphoma providing evidence to support these efforts. In addition, we propose a surveillance imaging strategy that uses a novel risk-adapted and response-based approach to determine which children would most benefit from off-therapy imaging surveillance.
Recommended Citation
Voss, S., & Cairo, M. (2019). Surveillance Imaging in Pediatric Lymphoma. Pediatric Radiology, 49 (11), 1565-1573. https://doi.org/10.1007/s00247-019-04511-4