Cardiac Resynchronization Therapy for Heart Failure

Authors

Amole Ojo
Sohaib Tariq
Prakash Harikrishnan, New York Medical CollegeFollow
Sei Iwai, New York Medical CollegeFollow
Jason T. Jacobson, New York Medical CollegeFollow

DOI

10.1016/j.iccl.2017.03.010

Journal Title

Interventional Cardiology Clinics

First Page

417

Last Page

426

Document Type

Article

Publication Date

7-1-2017

Department

Medicine

Keywords

Biventricular pacing; Cardiac resynchronization therapy; Dyssynchrony; Heart failure with reduced ejection fraction

Disciplines

Cardiology | Medicine and Health Sciences | Therapeutics

Abstract

Cardiac resynchronization therapy (CRT) has emerged as a valued nonpharmacologic therapy in patients with heart failure, reduced ejection fraction (EF), and ventricular dyssynchrony manifest as left bundle branch block. The mechanisms of benefit include remodeling of the left ventricle leading to decreased dimensions and increased EF, as well as a decrease in the severity of mitral regurgitation. This article reviews the rationale, effects, and indications for CRT, and discusses the patient characteristics that predict response and considerations for nonresponders.

Recommended Citation

Ojo, A., Tariq, S., Harikrishnan, P., Iwai, S., & Jacobson, J. T. (2017). Cardiac Resynchronization Therapy for Heart Failure. Interventional Cardiology Clinics, 6 (3), 417-426. https://doi.org/10.1016/j.iccl.2017.03.010

Publisher's Statement

Originally published in Interventional Cardiology Clinics, 6 (3), 417-426. The original material can be found here.