NYMC Faculty Publications

Complex Abdominal Wall Hernia Repair with Biologic Mesh in Elderly: a Propensity Matched Analysis

DOI

10.1007/s10029-019-02068-7

Journal Title

Hernia : the Journal of Hernias and Abdominal Wall Surgery

First Page

495

Last Page

502

Document Type

Article

Publication Date

6-2020

Department

Surgery

Keywords

Abdominal Wall, Acellular Dermis, Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Animals, Bioprosthesis, Female, Hernia, Ventral, Herniorrhaphy, Humans, Male, Middle Aged, Propensity Score, Reconstructive Surgical Procedures, Reoperation, Retrospective Studies, Risk Adjustment, Surgical Mesh, Young Adult

Disciplines

Medicine and Health Sciences | Surgery

Abstract

BACKGROUND: Complex abdominal wall reconstruction (CAWR) has become a common surgical procedure both in non-elderly and elderly patients.

OBJECTIVE: The aim of this study is to analyze the outcomes of the elderly compared to nonelderly undergoing CAWR using propensity score matching.

METHODS: All patients who underwent CAWR using porcine-derived, non-crosslinked acellular dermal matrix (ADM) (Strattice™) between January 2014 and July 2017 were studied retrospectively. Propensity matched analysis was performed for risk adjustment in multivariable analysis and for one-to-one matching. The outcomes were analyzed for differences in postoperative complications, reoperations, mortality, hospital length of stay and adverse discharge disposition.

RESULTS: One hundred-thirty-six patients were identified during the study period. Non-elderly (aged 18-64 years) constituted 70% (n = 95) and elderly (aged ≥ 65 years) comprised 30% of the overall patient population (n = 41). Seventy-three (56.7%) were females. After adjustment through the propensity score, which included 35 pairs, the surgical site infection (p = 1.000), wound necrosis (p = 1.000), the need for mechanical ventilation (p = 0.259), mortality (p = 0.083), reoperation rate (p = 0.141), hospital length of stay (p = 0.206), and discharge disposition (p = 0.795) were similar.

CONCLUSION: Elderly patients undergoing CAWR with biological mesh have comparable outcomes with non-elderly patients when using propensity matching score.

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