NYMC Faculty Publications

Stem Cell Therapy for Acute Myocardial Infarctions: A Systematic Review

DOI

10.1097/CRD.0000000000000291

Journal Title

Cardiology in Review

First Page

140

Last Page

147

Document Type

Article

Publication Date

5-2020

Department

Medicine

Abstract

Each year 790,000 people in the United States suffer from a myocardial infarction. This results in the permanent loss of cardiomyocytes and an irreversible loss of cardiac function. Current therapies lower mortality rates, but do not address the core pathology, which opens a pathway to step-wise heart failure. Utilizing stem cells to regenerate the dead tissue is a potential method to reverse these devastating effects. Several clinical trials have already demonstrated the safety of stem cell therapy. In this review, we highlight clinical trials, which have utilized various stem cell lineages, and discuss areas for future research.

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