Primary Aldosteronism: Cardiovascular Risk, Diagnosis, and Management

Authors

Padma Raghavan Pillai
Mindy Griffith
Monica D. Schwarcz
Irene A. Weiss, New York Medical CollegeFollow

Author Type(s)

Faculty

DOI

10.1097/CRD.0000000000000281

Journal Title

Cardiology in Review

First Page

84

Last Page

91

Document Type

Review Article

Publication Date

3-2020

Department

Medicine

Abstract

Primary aldosteronism remains a leading cause of secondary hypertension, and its diagnosis and management continue to pose a challenge for clinicians. In this article, we review the diagnosis of primary aldosteronism along with its cardiovascular manifestations. Treatment is described depending on the diagnostic outcome, focusing on medical management with mineralocorticoid receptor antagonists and unilateral adrenalectomy. Although screening and diagnosing hyperaldosteronism follows well-known algorithms, in practice, physicians may find difficulty establishing the best course of action due to complexity in testing and confirming laterality of aldosterone production by the adrenals. Recognizing and treating primary aldosteronism requires a multidisciplinary approach with primary care physicians, cardiologists, endocrinologists, and radiologists working collaboratively.

Recommended Citation

Pillai, P., Griffith, M., Schwarcz, M. D., & Weiss, I. A. (2020). Primary Aldosteronism: Cardiovascular Risk, Diagnosis, and Management. Cardiology in Review, 28 (2), 84-91. https://doi.org/10.1097/CRD.0000000000000281